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alendronate 35mg tablets

Alendronate is used to slow bone loss and boost bone density. After taking it, avoid lying down for at least 30 minutes. Only swallow tablet with a full glass (6 to 8 ounces) of water.

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Wait at least 30 minutes after taking an alendronate tablet before lying down. Alendronate works only if taken on an empty stomach. prior to taking other medications, such as antacids, calcium, and other dietary supplements and vitamins. before you consume your first meal or beverage (aside from plain water). Do not chew or suck on a tablet of alendronate. After taking alendronate and eating your first meal of the day, wait at least 30 minutes before lying down. Do not lie down. Do not take 2 doses on the same day. Do not take alendronate with mineral water, coffee, tea, soda, or juice. Never attempt to throw up. Alendronate oral solution should be followed by at least 2 ounces of plain water. Alendronate effervescent tablet: Mix one tablet with about four ounces of plain, room-temperature water to dissolve. Do not take alendronate again in the same day if you miss a dose. If you take alendronate regularly, take 1 tablet of the medication once daily, right after you wake up and before you consume your first meal, beverage, or medication. When taking alendronate only once per week, pick the day of the week that works best for your schedule. Immediately contact your physician if you take too much alendronate. Oral Solution: Drink your prescribed dose every week on your chosen day after you get up for the day and before taking your first food, drink, or other medicine. Tablets: After getting up for the day and before consuming your first meal, beverage, or dose of another medication, take 1 dose of alendronate once a week with water. After waking up for the day, take alendronate before consuming your first meal, beverage, or medication. Follow your doctor's instructions when taking alendronate. As you are sitting or standing, take alendronate. Once you remember, take the missed dose the following morning, and then go back to your regular schedule. When the effervescence stops, wait at least five minutes before drinking the solution. You can read while you sit, stand, or walk around.


Swirl the glass gently with a little more water added before immediately drinking it. Alendronate is often given for only 3 to 5 years. Alendronate is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Alendronate is taken either once daily or once per week. Regularly floss and brush your teeth. Information on the dosage of Alendronate in detail The effervescent tablet should be dissolved in at least 4 ounces of water (at room temperature—not hot or cold). Do not crush, chew, or suck on an alendronate regular tablet. Other than pure water, avoid eating or drinking anything. Avoid lying or reclining. Take no other medications, not even antacids, calcium supplements, or vitamins. Do not use coffee, tea, soda, juice, or mineral water. Read all medication guides or instructions before using any of the products listed on your prescription label. Carefully follow the dosing recommendations provided by your doctor. Observe your doctor's instructions exactly. Following the administration of alendronate, for at least 30 minutes: Inform the dentist in advance if you require any dental work, especially surgery, and let them know you are taking alendronate. If you only take alendronate once per week, make sure to take it on the same day every week and first thing in the morning. Keep unused effervescent tablets in the foil blister pack. 5 minutes are needed for the tablet to dissolve. Carefully dispense liquid medications. While taking alendronate, be especially mindful of your oral hygiene. After 10 seconds of stirring, immediately drink the entire mixture. Away from heat and moisture, store items at room temperature. Totally inhale it. Take alendronate first thing in the morning, at least 30 minutes before you eat, drink, or take any other medications. To be consumed with a full glass (6 to 8 ounces) of water. Use the provided dosing syringe or a dose-measuring medical device (not a kitchen spoon). Follow the medication's directions to the letter. How long you will be given this medication for treatment will be decided by your doctor.

Missed dose

Not two doses in a single day. Do not take two (2) doses in one day. Alendronate should be taken once daily. If you forget to take it in the morning, do not take it later in the day. Dosing instructions for once-weekly medications state that you should take alendronate as soon as you remember the missed dose, usually first thing in the morning of the next day. Then return to your regular weekly schedule on your chosen dose day. Skip the missed dose and wait until the next morning.


However, if overdose is suspected, seek emergency medical attention. An overdose is unlikely to happen if alendronate is given by a healthcare professional in a hospital setting. Call your doctor, your local poison control center, or get immediate emergency medical help if you take too much alendronate.


Never freeze an alendronate solution. This medication should not, however, be flushed down the toilet. A medicine take-back program is the preferable method for getting rid of your medication. All medications should be kept out of the sight and reach of children, as many containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for small children to open. Keep this medication tightly closed in its original container away from the reach of children. If you do not have access to a take-back program, visit the FDA's Safe Disposal of Medicines website at for more information. It should not be kept in the bathroom. Store it at room temperature, away from sources of extreme heat and moisture. For information on take-back programs in your neighborhood, speak with your pharmacist or get in touch with the waste/recycling department of your city. Always lock safety caps and immediately store medications up and away and out of young children's sight and reach. Unused medications should be disposed of in special ways to ensure that pets, children, and other people cannot ingest them.

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Side effects

Serious adverse reactions are possible with alendronate. Consult your doctor or pharmacist if you want more details. Check out "Drug Precautions." If any side effect bothers you or does not go away, let your doctor know right away. The following are the side effects of alendronate that are most frequently reported: Stomach area (abdominal) pain Heartburn Constipation Diarrhea Upset stomach Pain in your bones, joints, or muscles Nausea. You may also experience allergic reactions like hives or, in rare instances, swelling of your face, lips, tongue, or throat. Alendronate may have additional side effects in addition to these.


Drug interactions with alendronate (more information) More information on alendronate Side effects Drug interactions Dosage information During pregnancy or breastfeeding Reviews (140) Patient tips Drug images Compare alternatives Pricing & coupons Spanish Drug class: bisphosphonates Patient resources Advanced Reading Alendronate Effervescent Tablets Alendronate Tablets Alendronate Oral Solution Other brands Fosamax, Binosto Professional resources Prescribing Information Related treatment guides Prevention of Osteoporosis Osteoporotic fractures Osteoporotic fracture The list of potential drug interactions is not exhaustive. Aside from prescription and over-the-counter medications, vitamins, and herbal products, alendronate may also interact with other medications. Inform your doctor of all other medications you are taking, especially: This isn't a comprehensive list. NSAIDs (nonsteroidal anti-inflammatory drugs), such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others, also fall under the category of "NSAIDs."


Before beginning to take alendronate, a dentist should examine your teeth and carry out any necessary procedures, such as cleaning or repairing misfitting dentures. Also tell your doctor if you plan to become pregnant at any time in the future, because alendronate may remain in your body for years after you stop taking it. It's crucial that you and your doctor are aware that alendronate may be the cause of this type of pain, even though it may start after you've taken the medication for a while. Be sure to brush your teeth and clean your mouth properly while you are taking alendronate. Mention any of the following: cancer chemotherapy; or oral steroids like dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos). Angiogenesis inhibitors include bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), and sunitinib (Sutent). Inform your doctor and pharmacist if you have any allergies before taking alendronate, and also let them know if you take or plan to take any prescription and over-the-counter medicines, vitamins, dietary supplements, or herbal products. You should be aware that alendronate may cause osteonecrosis of the jaw (ONJ, a serious condition of the jaw bone), especially if you have dental surgery or treatment while taking the medication. If you become pregnant while receiving treatment or after, call your doctor right away. Call your doctor right away if you experience severe pain at any time during your treatment with alendronate. Alendronate may cause severe bone, muscle, or joint pain; therefore, consult your doctor before getting any dental work done while you are taking this medication. After taking alendronate for the first time, you might experience this pain days, months, or even years later. If you are taking any other medications, such as dietary supplements, vitamins, or antacids by mouth, take them at least 30 minutes after you take alendronate. tell your doctor if you are unable to sit upright or stand upright for at least 30 minutes, if you have or have ever had a low level of calcium in your blood, a risk of breathing in food or fluids into the lungs, or if you have any of the following conditions: Tell your doctor if you are undergoing radiation therapy, on a sodium-restricted diet (if taking the effervescent tablets), have or have ever had anemia (condition in which the red blood cells do not bring enough oxygen to all the parts of the body), difficulty swallowing, heartburn, ulcers or other stomach problems, cancer, any type of infection, especially HIV/AIDS. Your doctor may tell you to stop taking alendronate and your pain may go away after you stop taking the medication. talk to your doctor about other things you can do to prevent osteoporosis from developing or worsening. The most likely advice you'll receive from your doctor is to quit smoking, limit your alcohol intake, and engage in regular weight-bearing exercise.

What is alendronate sodium solution?

Alendronate Sodium Oral Solution is a bisphosphonate indicated for: • Treatment of osteoporosis in postmenopausal women (1.1) • Treatment to increase bone mass in men with osteoporosis (1.3)

How long does it take to work?

Alendronic acid usually starts to work after 1 month. However, it may take 6 to 12 months for the medicine to fully protect your bones.

Why is alendronate taken once a week?

Administering alendronate (70 mg) once a week effectively provides continuous inhibition of bone resorption because bone resorption by osteoclasts is a slow process that typically requires 2-3 weeks for completion and alendronate remains at active bone remodelling sites for a sustained period and (when present in ...

Is it safe to take long term?

Alendronic acid is generally prescribed for a long time. While you're taking it, you're less likely to break a bone. In a very small number of people, taking alendronic acid for more than 2 years can increase their chances of getting a rare type of bone damage in their inner ear and certain types of breaks to their thigh bones. For this reason, your doctor will look at the benefits and risks of your treatment after 3 to 5 years and decide whether you should keep taking alendronic acid. This may involve some tests to check the strength (density) of your bones. The benefits of taking alendronic acid generally outweigh the risks. If you're concerned or have any questions, talk to your doctor or pharmacist.

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Bala Mass Mar 12, 2013, 2:00:46 PM

In fact, bone biopsy studies from patients treated with risedronate or alendronate show that the mineralizing surface, which is forming bone, decreases 80% to 96% after 3 years of treatment. Effects of long-term risedronate on bone quality and bone turnover in women with postmenopausal osteoporosis. The bone volume, however, does not significantly change (2, 3).

joseph jones Dec 29, 2018, 1:41:49 PM

Osteoporosis, glucocorticoid-induced: Note: Recommended for use in males ≥50 years of age and postmenopausal females with low BMD (T-scores between −1 and −2.5 in either group) and expected to receive systemic glucocorticoid therapy for at least 3 months at a prednisone dose of ≥7.5 mg/day (or its equivalent); or in any patient whose baseline risk of fracture is high and is receiving a glucocorticoid at any dose or duration. Fixed dosing (Apkon 2008; Houston 2014; Sholas 2005): Children ≥6 years and Adolescents: Oral: Usual reported dose: 35 mg once weekly. Patients with T-scores between −1 and −2.5 and not at high fracture risk according to an assessment but who desire pharmacologic therapy for prevention of bone loss and/or fracture (Lewiecki 2019): Prevention: Oral: 35 mg once weekly or 5 mg once daily. Missed doses (once weekly): If a once-weekly dose is missed, administer the next morning after remembered; then return to the original scheduled day of the week on the once-weekly schedule; however, do not administer 2 doses on the same day. Due to uncertain efficacy relative to preferred agents, some experts recommend against the use of alendronate for this indication unless preferred agents are unavailable or inappropriate (Smith 2019).

yatsa Sep 14, 2020, 5:29:04 AM

Stand or sit up for at least 30 minutes after you take this medicine; do not lie down. They need to know if you have any of these conditions: esophagus, stomach, or intestine problems, like acid-reflux or GERD dental disease kidney disease low blood calcium low vitamin D problems swallowing problems sitting or standing for 30 minutes an unusual or allergic reaction to alendronate, other medicines, foods, dyes, or preservatives pregnant or trying to get pregnant breast-feeding How should I use this medicine? You should make sure you get enough calcium and vitamin D while you are taking this medicine, unless your doctor tells you not to. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

mrkmn Jul 18, 2013, 1:32:10 AM

• This drug-safety issue concerning Fosamax-related atypical femur fractures is discussed in the January 14, 2013 edition of the medical journal JAMA Internal Medicine (formerly Archives of Internal Medicine). Therefore, on the basis of our results, we cannot conclude that there is a potential risk of atypical fractures with [Actonel (risedronate)], [Boniva (ibandronate)], [Didronel (etidronate)], and [Zometa (zoledronic acid)] use, likely owing to a lack of statistical power. This January 2013 letter by Michael Pazianas, MD, seems to base its inquiry on this point: It is now well recognized that individual bisphosphonates differ in their pharmacological properties. Legal Information And News About Prescription Drug Side Effects (All website content by attorney Tom Lamb) Drug Injury Case Evaluation - Free & Confidential (Review done by attorney Tom Lamb) Indeed, these drugs were prescribed far less often than alendronate.

ahelix Sep 12, 2012, 7:36:11 PM

Currently available data for alendronic acid in the paediatric population is described in section 5.1. - Patients should not lie down for at least 30 minutes after taking FOSAMAX and until after the first food of the day. Other beverages (including mineral water), food and some medicinal products are likely to reduce the absorption of alendronate (see section 4.5). The optimal duration of bisphosphonate treatment for osteoporosis has not been established.

mpontillo Jul 18, 2010, 2:23:26 PM

Fosamax comes as 70-milligram (mg) tablets that you take by mouth, typically once a week. It’s FDA-approved for the following uses in adults: prevent or treat osteoporosis (a condition that causes brittle, weak bones) in females* who’ve gone through menopause treat osteoporosis in males* treat osteoporosis that’s caused by using a type of medication called glucocorticoids treat Paget’s disease of bone (a condition that causes weak, soft bones) Drug details Fosamax contains the active drug alendronate. Effectiveness For information on the effectiveness of Fosamax, see the “Fosamax uses” section below. Fosamax works to decrease bone breakdown in your body and make your bones stronger.

gonecasescenario Jan 6, 2017, 12:05:20 PM

It what is known record that Binosto (alendronate) may further exacerbate existing renal tubular dysfunction. Conjugated estrogens / medroxyprogesterone acetate may cause headache or tearing thousands of a tendon, especially if offering you are heading over 60, if you take steroid medication, or liquid if you have improved had a kidney, heart, or honeycomb lung transplant. Although a small minimum amount of each additional dose, dangerous substance treatment improved the osteopenia in both patients together work with an improvement of nocturnal urinary frequency.

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