Description
By reducing the parasite's ability to produce energy, albendazole causes degenerative changes in its intestinal and tegument cells, which ultimately cause the parasite to become immobile and die. As cytoplasmic microtubules are critical in promoting glucose uptake in larval and adult stages of the susceptible parasites, the glycogen stores of the parasites are depleted. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. By attaching to tubulin's colchicine-sensitive site, it prevents tubulin from polymerizing or assembling into microtubules, which is how it functions.
Dosage
It is possible to take albendazole orally as a tablet. Roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites—animals or plants that live inside other living things to gain an advantage—as well as other infections are occasionally treated with albendazole. Do not take more or less of it or take it more often than prescribed by your doctor. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. If you are giving the medication to a child or if you cannot swallow the tablets whole, you may crush or chew the tablets and swallow the medication with a drink of water. Your infection might not be completely treated if you stop taking albendazole too soon or skip doses. Usually, two times per day, it is taken with food. Every day, take albendazole around the same time. Take albendazole exactly as directed. Even if you feel better, continue taking albendazole until the medication is gone. The risks of using this medicine for your condition should be discussed with your doctor. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Continue eating normally unless your doctor instructs you otherwise. In order to effectively treat cystic hydatid disease, albendazole is typically administered in three cycles of 28 days of treatment, followed by a 14-day break. Neurocysticercosis is commonly treated with albendazole, which is typically taken for 8 to 30 days.
Missed dose
To make up for a missed dose, don't take a second one. To continue with your regular dosing schedule, skip the missed dose if it is almost time for the next one. As soon as you remember, take the missed dose.
Overdose
Call 911 right away if the victim has fallen, experienced a seizure, is having trouble breathing, or cannot be roused. Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help.
Storage
However, you should not flush this medication down the toilet. The best way to get rid of your medication is instead through a medication take-back program. All medications should be kept out of the sight and reach of children, as many containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for small children to open. Store this medication out of children's reach in the tightly closed, original container. If you are unable to participate in a take-back program, visit the FDA's Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for more details. Keep it at room temperature and out of the bathroom and other places with excessive heat and moisture. For information on take-back programs in your neighborhood, speak with your pharmacist or get in touch with the waste/recycling department of your city. http://www.upandaway.org Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Always lock safety caps and place the medication in a safe location - one that is up and away and out of their sight and reach.
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Accessed 14 August 2018 2 Centers for Disease Control and Prevention. GSK Philippines General Manager, Sriram Jambunathan, commented, “The Philippine Government, through the DOH, is to be commended for its achievement in the elimination of LF in many provinces in the last two decades. Reference: 1 Department of Health (Philippines) official Facebook page. Available at: http://www.cdc.gov/parasites/lymphaticfilariasis/epi.html Accessed June 2018 4 World Health Organization. Accessed June 2018 5 Kron M, Walker E, Hernandez L, Torres E, Libranda-Ramirez B. Parasitol Today.
Presentation: • Blister of 1 tablet & Blister of 2 tablets. Pharmacological Action: • Albendazole is a benzimidazole carbamate with anthelmintic and antiprotozoal activity against intestinal and tissue parasites.Animal studies have shown that albendazole exhibits vermicidal, ovacidal, and larvacidal activity.Rworm has been shown to be effective in the treatment of Giardia infections in children. The tablets may be chewed, swallowed or crushed and mixed with food. Albendazole has not been adequately studied in children under one year of age.
Fifty-six hours after ingesting raccoon feces, Martin and Haughton's son received his first dose of albendazole. 'I just felt something grab my leg': Calgary woman describes coyote attack that sent her to hospital with bite After rushing their son to a hospital emergency room, they were prescribed albendazole, which needs to be taken within three days of exposure. The life-saving medicine she needs is cheap, common and unavailable in Canadian pharmacies It had not compounded the anti-parasitic formula in more than a decade, but it had the medication and the ingredients needed to make it into a palatable liquid. Martin and Haughton, meanwhile, were preparing to drive to Montana to get the drug when they learned the Calgary pharmacy could make it. "I've got young kids, and I couldn't imagine being in that situation," said Barry, who works at Shoppers Drug Mart in Park Place Mall.
Albendazole Oral Suspension • Product Description: Albendazole is being used to treat lymphatic filariasis as part of efforts to stop transmission of intestinal worm diseases. Albendazole has larvicidal effects in necatoriasis and ovicidal effects in ascariasis, ancylostomiasis, and trichuriasis. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Product Packaging – The dosages available for this product are: • Albendazole Oral Suspension 2.5% Albendazole Oral Suspension 10% Albendazole Oral Suspension can be packaged as 100ml/vial, 120ml/vial, 250ml/vial, 500ml/vial, 1 Liter per bottle, or as per customer requirement. In sub-Saharan Africa, albendazole is used in conjunction with ivermectin, and elsewhere in the world, the medicine is used in combination with diethylcarbamazine.
See the Guidelines for complete information on recommended uses of albendazole in adults and adolescents with HIV. The recommended uses may not always be consistent with FDA-approved uses of albendazole. Albendazole may also be recommended for use in other rare circumstances not listed above. The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV include recommendations on the uses of albendazole to treat microsporidiosis, including intestinal and disseminated infection caused by certain types of microsporidia and ocular (eye) infection.