Serious adverse reactions are possible with Actonel. For more details, consult your physician or pharmacist. Examine "Drug Precautions." If you experience any side effect that is bothersome or does not go away, let your doctor know. The most common side effects of Actonel are: pain, including back and joint pain stomach area (abdominal) pain heartburn Actonel can cause allergic reactions, such as hives or, in rare cases, swelling of your face, lips, tongue, or throat. Actonel side effects are not all included in this list.
Ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), aspirin, antacids, proton pump inhibitors (esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), H2 blockers (cimetidine (Tagamet), famotidine (Pepcid), Inform your doctor about every medication you take, including any over-the-counter, prescription, and herbal supplements.
1. Actonel has the potential to cause issues with the esophagus, which connects the throat and stomach. Actonel can cause low calcium levels in your blood (hypocalcemia), which can worsen already low blood calcium conditions. If you experience any of these side effects, contact your doctor right away. If you: cannot stand or sit up straight for at least 30 minutes; have low calcium levels in your blood; or are allergic to Actonel or any of its ingredients, do not take Actonel. If you have low blood calcium before taking Actonel it must be treated before you take Actonel. It is important that you take Actonel exactly as prescribed to help lower your chance of getting esophagus problems including: irritation inflammation ulcers of the esophagus which may sometimes bleed Stop taking Actonel and call your doctor right away if you have painful or difficult swallowing, chest pain, or new or worsening heartburn. 2. When taking Actonel, you run the risk of developing severe jaw bone issues. Unusual thigh bone fractures have occurred in a few people. Actonel users occasionally experience severe muscle, joint, or bone pain. The hip, groin, or thigh may experience new or unusual pain as a result of a fracture. As directed by your doctor, consume calcium and vitamin D. 3. You may not know you have low blood calcium, but some people may have the following symptoms: Spasms, twitches, or cramps in your muscles Numbness or tingling in your fingers, toes, or around your mouth Your doctor may prescribe calcium and vitamin D to help prevent low calcium levels in your blood, while you take Actonel. Before you start Actonel, your doctor and dentist may perform a mouth exam.