Call your doctor if you experience any side effects that bother you or that do not go away, such as dry skin chapped lips dry eyes and a dry nose that can cause nosebleeds. See the section on "Accutane Precautions." Accutane is known to have serious side effects.
Drug interactions with accutane (more information) John's wort (which may reduce the effectiveness of birth control pills); vitamin or mineral supplements; progestin-only birth control pills (mini-pills, which may not work as well when taken with isotretinoin); steroid medication; or a tetracycline antibiotic, such as doxycycline or minocycline. Not all possible drug interactions are listed here. Prescription and over-the-counter medications, vitamins, and herbal products, among others, may interact with isotretinoin. Tell your doctor about all your other medicines, especially: This is not a comprehensive list. Phenadol; St.
Birth defects (deformed babies), miscarriages, infant deaths, and early (premature) births are just a few of the serious side effects that Accutane can produce. Birth defects brought on by Accutane are severe. Serious mental health issues may result from taking Accutane. If you or a family member notices that you are exhibiting any of the following symptoms of depression or psychosis, stop taking Accutane and contact your doctor right away. Depression Psychosis (seeing or hearing things that are not real) Suicide. In adolescents who are still developing, accutane may stop the growth of long bones. If you experienced any of these side effects while taking Accutane, you might also need follow-up mental health care. And some people have ended their own lives. start to feel sad or have crying spells lose interest in activities you once enjoyed sleep too much or have trouble sleeping become more irritable, angry, or aggressive than usual (for example, temper outbursts, thoughts of violence) have a change in your appetite or body weight have trouble concentrating withdraw from your friends or family feel like you have no energy have feelings of worthlessness or guilt start having thoughts about hurting yourself or taking your own life (suicidal thoughts) start acting on dangerous impulses start seeing or hearing things that are not real Other serious side effects: Serious brain problems: Accutane can increase the pressure in your brain. Accutane is only prescribed to patients who are able to comprehend and consent to follow all of the instructions in the iPLEDGE program because it has the potential to cause birth defects. Diabetes and other blood sugar issues may be brought on by accutane. Bone and muscle problems: Accutane may affect bones, muscles, and ligaments and cause pain in your joints or muscles. Reduced red and white blood cells: If you have trouble breathing, feel faint, or are weak, call your doctor right away. If you have an allergy to any component of Accutane, do not use it. If you are pregnant, intend to become pregnant, or already are pregnant, you should not take Accutane. All cases of pregnancy should be reported to the FDA MedWatch at 1-800-FDA-1088, the iPLEDGE pregnancy registry at 1-866-495-0654, and the FDA for 1 month before starting Accutane, while taking Accutane, and for 1 month after stopping Accutane. Women taking Accutane must not become pregnant; if you do, stop taking the medication immediately and contact your doctor. Female patients who are pregnant or who plan to become pregnant must not take Accutane. Problems hearing: If your hearing deteriorates or if you experience ringing in your ears, stop taking Accutane and contact your doctor. When taking Accutane and after treatment, contact lens wearers may experience difficulties. Even after you stop taking Accutane, your organs might not heal if they have been harmed. A rash may be serious in some patients. Lipid issues: Accutane can make your blood fat and cholesterol levels higher. Painless or painful muscle weakness may indicate severe muscle damage. Other harmful eye effects could also happen. Visit your doctor again for blood tests to check your lipids and receive any necessary treatment. Serious allergic reactions: If you experience hives, a swollen face or mouth, difficulty breathing, or other symptoms, stop taking Accutane immediately and seek emergency medical attention. Suicidal thoughts have been reported in some Accutane users. Some people made an attempt at suicide. Problems with the stomach (abdomen): Some symptoms could indicate damage to your internal organs. If you experience muscle weakness while taking Accutane, stop immediately and contact your doctor. If you develop a fever, rash, red patches, or bruises on your legs, stop taking Accutane and contact your doctor right away. Call your doctor and stop taking Accutane if you experience any of the following symptoms: intense stomach, chest, or bowel pain; difficulty swallowing; swallowing that hurts; heartburn that is new or getting worse; diarrhea; rectal bleeding; yellowing of your skin or eyes; or dark urine. Stop taking Accutane and call your doctor right away if you get any of these signs of increased brain pressure: bad headache blurred vision dizziness nausea or vomiting seizures (convulsions) stroke Skin problems: Skin rash can occur in patients taking Accutane. Stop taking Accutane and call your doctor right away if you have any problems with your vision or dryness of the eyes that is painful or constant. Conjunctivitis (red or inflamed eyes, like "pink eye"), a rash with a fever, blisters on the legs, arms, or face, and/or sores in your mouth, throat, nose, or eyes, as well as if your skin starts to peel are all signs that you should stop taking Accutane and contact your doctor right away. Tell all healthcare providers that you take Accutane if you break a bone. If you urinate a lot or are extremely thirsty, let your doctor know. If you experience back pain, joint pain, or a broken bone, tell your doctor. Inform your doctor if you intend to engage in strenuous exercise while taking Accutane. The liver, pancreas, bowel (intestines), and esophagus (the passageway between the mouth and the stomach) are among these organs. These problems usually go away when Accutane treatment is finished. This could be a very serious issue. This may cause a permanent loss of vision and, in extreme circumstances, death. This condition usually clears up after you stop taking Accutane, but it may be permanent. Accutane may impair your ability to see in the dark, causing vision problems. Your diminished hearing might be permanent.